Genus develops first porcine virus resistant pigs

Genus has developed the first pigs resistant to porcine reproductive and respiratory syndrome virus (PRRSv), through a long-standing collaboration with the University of Missouri.

The animal genetics company said the production of these pigs is a significant breakthrough in combating the “devastating” porcine disease, which can cause persistent infection in pigs and lead to reproductive failure, reduced growth and premature death.

There is currently no cure for the disease, which is considered to be the most economically burdensome viral disease of pig farms in Asia, Europe and North America.

Genus said that using precise gene editing, the University of Missouri was able to breed pigs that do not produce a specific protein necessary for the virus to spread in the animals.

The early stage studies conducted by the University demonstrate these PRRSv resistant pigs, when exposed to the virus, do not get sick and continue to gain weight normally.

Genus said it will continue to develop this technology, and expects it will be at least five years until PRRS-resistant animals are available to farmers.

Genus intends to commercialise the technology through ts porcine division, PIC.

Jonathan Lightner, chief scientific officer and head of research and development at Genus, said: “The demonstration of genetic resistance to the PRRS virus by gene editing is a potential game-changer for the pork industry.

“There are several critical challenges ahead as we develop and commercialise this technology; however, the promise is clear, and Genus is committed to developing its potential.”