Capital Markets Day & Notice of trading update

hVIVO plc

("hVIVO", the "Company" or the "Group")

Capital Markets Event and Trading Update on 17 July

hVIVO plc (AIM & Euronext: HVO), a fast growing specialist contract research organisation (CRO) and world leader in testing infectious and respiratory disease products using human challenge clinical trials, announces that it will be holding a Capital Markets Event at the Company's new state-of-the-art facility in Canary Wharf for analysts, institutional investors, and media on Wednesday 17 July 2024 at 10.00 am - 12.30 pm (BST). The Company also expects to announce a trading update for the six months ended 30 June 2024 on the same day.

The event will focus on the capabilities of the world's largest human challenge trial unit and how it will enhance and broaden hVIVO's services, as well as covering the Group's trading update. CEO Yamin 'Mo' Khan will chair the event that will include speakers from across the Group, as well as a fireside chat with a number of external speakers discussing the utility of human challenge trials. There will also be an opportunity for attendees to take part in Q&A sessions with the speakers and to tour the laboratory and challenge trial unit.

Analysts, institutional investors and media are welcome to attend the in-person event. Due to restrictions on numbers, it will not be possible for all interested parties to attend in-person, however, a live webcast will be available on the Company's website for retail investors and others to view the presentations here.

To register your interest for the event or webcast, please contact Walbrook PR on +44 20 7933 8780 or email [email protected]. A recording of the presentation will be made available on the Company's website after the event.

For further information please contact:

Notes to Editors

About hVIVO

hVIVO plc (ticker: HVO) (formerly Open Orphan plc) is a fast growing specialist contract research organisation (CRO) and the world leader in testing infectious and respiratory disease vaccines and therapeutics using human challenge clinical trials. The Group provides end-to-end early clinical development services to its large, established and growing repeat client base, which includes four of the top 10 largest global biopharma companies.

The Group's fast-growing services business includes a unique portfolio of 11 human challenge models, with a number of new models under development, to test a broad range of infectious and respiratory disease products. The Group has world class challenge agent manufacturing capabilities, specialist drug development and clinical consultancy services via its Venn Life Sciences brand, and a lab offering via its hLAB brand, which includes virology, immunology biomarker and molecular testing. The Group offers additional clinical field trial services such as patient recruitment and clinical trial site services.

hVIVO runs challenge trials in London - its new state-of-the-art facilities in Canary Wharf opened in 2024 and is the world's largest commercial human challenge trial unit, with highly specialised on-site virology and immunology laboratories, and an outpatient unit. To recruit volunteers / patients for its studies, the Group leverages its unique clinical trial recruitment capability via its FluCamp volunteer screening facilities in London and Manchester.