* Value is calculated by using the current share price multiplied by the amount held.
Major Shareholdings
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Notifier**
Holding
Value
Redmile Group, LLC
268,616,936
£26,861,694.00
VULPES LIFE SCIENCES FUND
117,729,029
£11,772,903.08
VULPES LIFE SCIENCES FUND
117,479,029
£11,747,903.08
Ferlim Nominees Limited
50,632,079
£5,063,207.98
Reyker Nominees Ltd
48,464,691
£4,846,469.17
** Major Shareholders are individuals or institutions that own more than 3% of the company’s shares and have been reported in the annual accounts.
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