Posting of Circular & Notice of GM

Renalytix plc

("Renalytix" or the "Company")

Posting of Circular

and

Notice of General Meeting

LONDON and NEW YORK, 11 October, 2024  ̶  Renalytix plc (LSE: RENX) (OTCQB: RNLXY), an artificial intelligence-enabled in vitro diagnostics company, focused on optimizing clinical management of kidney disease to drive improved patient outcomes and advance value-based care, confirms that, further to the Company's announcement released at 11:02 on 1 October 2024 (RNS Number: 4887G), the Circular, containing the Notice of the General Meeting, which sets out the Resolutions and further details on the Fundraising, has been posted to Shareholders and is available on the Company's website at https://renalytix.com.

The General Meeting to approve the Resolutions will be held at 6 Stratton Street, Mayfair, London, W1J 8LD at 12.00 noon on 31 October 2024.

The Circular includes a unanimous Board recommendation that all Shareholders of the Company vote in favour of the Resolutions.

For further information, please contact:

The person responsible for making this Announcement on behalf of the Company is

James McCullough, Chief Executive Officer.

About Renalytix plc

Renalytix (LSE: RENX) (OTCQB: RNLXY) is an artificial intelligence enabled in-vitro diagnostics and laboratory services company that is the global founder and leader in the field of bioprognosis™ for kidney health. In late 2023, our kidneyintelX.dkd test was recognized as the first and only FDA-authorized prognostic test to enable early-stage CKD (stages 1-3b) risk assessment for progressive decline in kidney function in T2D patients. By understanding how disease will progress, patients and clinicians can take action earlier to improve outcomes and reduce overall health system costs. For more information, visit www.renalytix.com.